Description

2-Methylpropanoic acid (1aR,3S,4Z,5aR,8aR,9R,10aR)-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-3-hydroxy-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester is a high-purity, complex organic ester derivative of 2-methylpropanoic acid, valued for its specific stereochemistry and functional groups. This compound is a critical advanced intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and synthesis of novel drug candidates, especially in oncology and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new, more effective pesticides and herbicides due to its complex, bioactive scaffold.
• Fine Chemical Synthesis: Serves as a versatile intermediate for producing specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic synthesis and natural product chemistry.
• Process Chemistry Development: Used to optimize scalable synthetic routes for the production of high-value target molecules.

Basic Information

Item	Details
Product Name	2-Methylpropanoic acid (1aR,3S,4Z,5aR,8aR,9R,10aR)-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-3-hydroxy-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester
CAS No.	59979-58-7
Molecular Formula	C20H28O6
Molecular Weight	364.44 g/mol
Synonyms	Artemisinin Isobutyrate; Dihydroartemisinin Isobutyrate Ester; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol Isobutyrate; Arteether Related Compound; 10-Deoxoartemisinin Isobutyrate; Dihydroartemisinin 3-Isobutyrate; 3α-Isobutyryloxy-dihydroartemisinin
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Optical Rotation	Specific range provided on COA
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.