Description

9H-7,14b-Methano-1H-pyrano[2'',3'':4',5']benzofuro[2',3':4,5]oxocino[3,2-b][1]benzopyran-6(7H)-one, 3-(3,4-dihydroxyphenyl)-2,3,8a,14a-tetrahydro-2,7,10,12,17-pentahydroxy-, (2S,3R,7R,8aS,14aS,14bR)- is a complex, high-purity polyphenolic compound of significant interest in advanced research and development. This compound, known commercially as Procyanidin C1, is valued for its potent biological activity and serves as a critical reference standard and active ingredient. It is primarily sought by the pharmaceutical, nutraceutical, and cosmetic industries for applications in antioxidant formulations, anti-aging research, and metabolic health studies.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification and quantification of procyanidins in drug development and quality control (QC) testing.
• Nutraceutical Ingredient: Incorporated into dietary supplements targeting oxidative stress, cardiovascular health, and metabolic syndrome due to its high antioxidant capacity.
• Cosmetic Actives: Formulated into anti-aging serums, creams, and lotions for its protective effects against UV-induced skin damage and collagen degradation.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate mechanisms of action related to inflammation, cell signaling, and neuroprotection.
• Functional Food & Beverage Additive: Used to enhance the health profile of beverages, chocolates, and other polyphenol-rich food products.
• Natural Product Isolation & Analysis: Serves as a benchmark for the extraction, purification, and analytical method development (e.g., HPLC, LC-MS) of oligomeric procyanidins from plant sources like grape seed, cocoa, and apples.

Basic Information

Item	Details
Product Name	9H-7,14b-Methano-1H-pyrano[2'',3'':4',5']benzofuro[2',3':4,5]oxocino[3,2-b][1]benzopyran-6(7H)-one, 3-(3,4-dihydroxyphenyl)-2,3,8a,14a-tetrahydro-2,7,10,12,17-pentahydroxy-, (2S,3R,7R,8aS,14aS,14bR)-
CAS No.	36048-23-4
Molecular Formula	C45H36O18
Molecular Weight	864.76 g/mol
Synonyms	Procyanidin C1; Procyanidin C-1; Procyanidin trimer C1; Epicatechin-(4β→8)-epicatechin-(4β→8)-epicatechin; [4,8]-Bi-epicatechin-(4β→8)-epicatechin; 1,2,3-Propanetriol, 1-[(2R,3R)-5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl]-3-[(2R,3R)-5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl]oxy]-2-[(2R,3R)-5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl]oxy]-; (+)-Catechin-(4α→8)-(-)-epicatechin-(4β→8)-(-)-epicatechin (obsolete); Oligomeric Procyanidin (OPC) C1
EINECS	Contact for details

Quality Control

Our Procyanidin C1 (CAS 36048-23-4) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and production use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We support compliance with ICH guidelines for stability and impurity profiling.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use (under one month), storage at 2-8°C is acceptable. This compound is easily oxidized and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with reference
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%
Water Content (KF)	≤3.0%
Residual Solvents (GC)	Complies with ICH Q3C Class 2/3 limits
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.