Description

1H-Benzimidazolium,5-cyano-2-[3-[5-cyano-1-ethyl-1,3-dihydro-3-(3-sulfopropyl)-2H-benzimidazol-2-ylidene]-1-propenyl]-1-ethyl-3-(3-sulfopropyl)-, inner salt, sodium salt is a specialized, high-purity cyanine dye intermediate with a complex polymethine structure. This compound is critical for its role in synthesizing near-infrared (NIR) fluorescent dyes and sensitizers, offering exceptional photostability and tunable absorption/emission properties. It is primarily needed by manufacturers in the biotechnology, medical diagnostics, and advanced materials sectors for developing next-generation imaging agents and optical materials.

Application

• NIR Fluorescent Dye Synthesis: A key precursor for producing heptamethine cyanine dyes used in bioimaging, flow cytometry, and in vivo diagnostics.
• Optical Sensitizer Production: Used in the manufacture of spectral sensitizers for photographic emulsions and digital imaging sensors.
• Laser Dye Intermediates: Serves as a building block for dyes utilized in tunable dye lasers and other photonic applications.
• Bioconjugation Reagents: Employed to create labeled probes and conjugates for immunoassays, fluorescence microscopy, and DNA sequencing.
• Photodynamic Therapy (PDT) Agents: A critical intermediate in the development of photosensitizers for targeted cancer therapies.
• Non-Linear Optical Materials: Used in research and production of materials for optoelectronics and photovoltaics.
• Analytical Chemistry Standards: Acts as a high-purity reference standard for quality control in dye and pigment manufacturing.

Basic Information

Item	Details
Product Name	1H-Benzimidazolium,5-cyano-2-[3-[5-cyano-1-ethyl-1,3-dihydro-3-(3-sulfopropyl)-2H-benzimidazol-2-ylidene]-1-propenyl]-1-ethyl-3-(3-sulfopropyl)-, inner salt, sodium salt
CAS No.	33628-08-9
Molecular Formula	C₃₄H₃₈N₆O₆S₂•Na
Molecular Weight	721.81 g/mol (as sodium salt)
Synonyms	IR-780 iodide related intermediate; Heptamethine cyanine dye intermediate; 5-Cyano-2-[3-(5-cyano-1-ethyl-1,3-dihydro-3-(3-sulfopropyl)-2H-benzimidazol-2-ylidene)-1-propenyl]-1-ethyl-3-(3-sulfopropyl)benzimidazolium hydroxide, inner salt, sodium salt; Benzimidazolium, 5-cyano-2-[3-[5-cyano-1-ethyl-1,3-dihydro-3-(3-sulfopropyl)-2H-benzimidazol-2-ylidene]-1-propenyl]-1-ethyl-3-(3-sulfopropyl)-, hydroxide, inner salt, sodium salt; NIR dye precursor; Sulfonated cyanine dye salt
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazolium cyanine dye intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and elemental analysis, to ensure it meets the exacting standards required for sensitive applications like bioconjugation and medical diagnostics. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Dark green to blue-black powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.