Description

(1S)-1,2,3,4a,9a,10-Hexahydro-2β,5,10α-trihydroxy-6-[(9,10-dihydro-1,8-dihydroxy-5-acetyl-6-methyl-9,10-dioxoanthracen)-2-yl]-2-methyl-1β-[(R)-1-acetoxyethyl]-4aα,9aα-epoxyanthracene-4,9-dione is a complex, high-purity anthraquinone derivative with significant biological activity. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical agents, particularly in oncology research. It is primarily sought by research institutions and pharmaceutical development companies for use in drug discovery and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel chemotherapeutic agents and targeted cancer therapies.
• Biochemical Research: Used as a reference standard and probe compound in studies of enzyme inhibition and cellular signaling pathways.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) with anthracycline-like structures.
• Academic Research: Employed in university and institutional labs for investigating structure-activity relationships (SAR) of polycyclic compounds.
• Preclinical Studies: Utilized in the development and testing of new drug candidates in animal models.

Basic Information

Item	Detail
Product Name	(1S)-1,2,3,4a,9a,10-Hexahydro-2β,5,10α-trihydroxy-6-[(9,10-dihydro-1,8-dihydroxy-5-acetyl-6-methyl-9,10-dioxoanthracen)-2-yl]-2-methyl-1β-[(R)-1-acetoxyethyl]-4aα,9aα-epoxyanthracene-4,9-dione
CAS No.	31498-89-2
Molecular Formula	C₃₈H₃₄O₁₄
Molecular Weight	714.67 g/mol
Synonyms	Daunorubicin aglycone derivative; 4-Demethoxydaunorubicinone derivative; 13-Deoxydoxorubicinone; 4-Demethoxy-13-dihydrodaunorubicinone; 4-DMDR; (1S)-1,2,3,4a,9a,10-Hexahydro-2β,5,10α-trihydroxy-2-methyl-1β-[(R)-1-acetoxyethyl]-4aα,9aα-epoxyanthracene-4,9-dione 6-yl derivative; Anthracycline intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and potency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to orange-red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.