Description

6,10-Dibenzyl-N,N'-dimethyl-N,N,N',N'-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane-(2R,3R)-diylbis(methylammonium) Bis(tetrafluoroborate) [=(R,R)-TaDiAS-2nd] is a sophisticated, chiral quaternary ammonium salt designed as a highly selective phase-transfer catalyst. This compound matters for enabling critical asymmetric synthesis reactions with exceptional enantioselectivity and yield, which are paramount for producing high-value, optically pure intermediates. It is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for scalable manufacturing.

Application

• Asymmetric Phase-Transfer Catalysis (PTC): Key for enantioselective alkylation, Michael addition, and epoxidation reactions under mild conditions.
• Pharmaceutical Intermediate Synthesis: Production of chiral active pharmaceutical ingredients (APIs) and key synthons for CNS drugs, antivirals, and cardiovascular agents.
• Agrochemical Manufacturing: Synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Catalyst for creating specialty flavors, fragrances, and advanced material precursors.
• Academic & Industrial R&D: A valuable tool for method development and exploring new asymmetric transformations in organic chemistry.
• Process Chemistry Optimization: Enables more efficient, cost-effective, and environmentally friendly (greener) synthetic routes on pilot and commercial scales.

Basic Information

Product Name	6,10-Dibenzyl-N,N'-dimethyl-N,N,N',N'-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane-(2R,3R)-diylbis(methylammonium) Bis(tetrafluoroborate) [=(R,R)-TaDiAS-2nd]
CAS No.	2010983-27-2
Molecular Formula	C66H82B2F8N2O2
Molecular Weight	1109.00 g/mol (Contact for details)
Synonyms	(R,R)-TaDiAS-2nd; (R,R)-TaDiAS-2nd Tetrafluoroborate; (2R,3R)-TaDiAS-2nd BF4 Salt; N,N'-Dimethyl-N,N,N',N'-tetrakis(4-methylbenzyl)-6,10-dibenzyl-1,4-dioxaspiro[4.5]decane-2,3-bis(methylammonium) bis(tetrafluoroborate); Chiral Spirocyclic Ammonium Salt; Asymmetric PTC Catalyst; Phase Transfer Catalyst (R,R)-TaDiAS-2nd
EINECS	Contact for details

Quality Control

Every batch of our (R,R)-TaDiAS-2nd catalyst is produced and tested under strict quality management protocols to ensure exceptional purity and consistent catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and residual solvent content. Our quality systems support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider handling under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.