Description

2-[2-[2-Chloro-3-[2-[1,3-dihydro-1-(4-sulfobutyl-2H-quinolinylidene) ethylidene]-1-cyclopentene-1-yl]ethenyl]-1(4-sulfobutyl)quinolinium], inner salt, monosodium salt is a high-purity, functional cyanine dye derivative, also known as a heptamethine cyanine salt. This compound is valued for its strong near-infrared (NIR) absorption and fluorescence properties, making it a critical component in advanced diagnostic and imaging applications. It is primarily sought by manufacturers and research institutions in the life sciences, biotechnology, and medical diagnostics sectors for developing sensitive assays and optical imaging agents.

Application

• Fluorescent Labeling Agent: Used as a covalent or non-covalent tag for biomolecules (e.g., proteins, antibodies, nucleic acids) in fluorescence-based bioassays.
• NIR Imaging Probes: A key component in the synthesis of contrast agents for in vivo and in vitro optical imaging, including fluorescence-guided surgery.
• Diagnostic Reagents: Incorporated into kits for clinical diagnostics, such as immunoassays and molecular diagnostics, due to its high molar absorptivity and photostability.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer in cancer research and treatment development.
• Sensor Development: Utilized in the fabrication of chemical and biological sensors that operate in the near-infrared spectrum to minimize background interference.
• Material Science: Acts as a functional dye for advanced materials, including optical filters, laser dyes, and non-linear optical materials.

Basic Information

Product Name	2-[2-[2-Chloro-3-[2-[1,3-dihydro-1-(4-sulfobutyl-2H-quinolinylidene) ethylidene]-1-cyclopentene-1-yl]ethenyl]-1(4-sulfobutyl)quinolinium], inner salt, monosodium salt
CAS No.	287183-28-2
Molecular Formula	C41H44ClN2NaO6S2
Molecular Weight	791.37 g/mol
Synonyms	IR-780 iodide analog (sulfobutyl); Heptamethine cyanine dye, sulfonated; Cy7.5 derivative; NIR-797; 1-(4-Sulfobutyl)-2-[2-[2-chloro-3-[(1,3-dihydro-1-(4-sulfobutyl)-2H-quinolin-2-ylidene)ethylidene]-1-cyclopenten-1-yl]ethenyl]quinolinium, hydroxide, inner salt, monosodium salt; Quinolinium, 1-(4-sulfobutyl)-2-[2-[2-chloro-3-[(1,3-dihydro-1-(4-sulfobutyl)-2H-quinolin-2-ylidene)ethylidene]-1-cyclopenten-1-yl]ethenyl]-, hydroxide, inner salt, monosodium salt
EINECS	Contact for details

Quality Control

Our production of this cyanine dye adheres to strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and spectral properties is provided with every shipment. We support development under GMP-like conditions for applications requiring regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to blue-black solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
λmax (Absorption)	780 - 800 nm (in methanol)
Moisture Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.