Description

1,5-cyclooctadiene{(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-(i-propyl)oxazole}iridiuM(I) tetrakis[3,5-bis(trifluoroMethyl)phenyl]borate, 97% (R,S)-(COD)Ir[iPr is a high-purity, chiral iridium-based organometallic complex designed for advanced asymmetric catalysis. This compound is a critical precatalyst for enantioselective transformations, offering researchers and process chemists a powerful tool to construct complex chiral molecules with high selectivity. It is essential for R&D and production in the pharmaceutical and fine chemical industries, where precise stereochemical control is paramount.

Application

• Asymmetric Hydrogenation: A key precatalyst for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral intermediates.
• Pharmaceutical Intermediate Synthesis: Enables the efficient and selective synthesis of chiral active pharmaceutical ingredients (APIs) and key building blocks.
• Fine Chemical Manufacturing: Used in the production of high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for developing new catalytic methodologies and exploring novel reaction pathways in organic synthesis.
• Chiral Ligand Screening: Serves as a precursor for generating active catalytic species in situ for screening and optimization studies.

Basic Information

Product Name	1,5-cyclooctadiene{(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-(i-propyl)oxazole}iridiuM(I) tetrakis[3,5-bis(trifluoroMethyl)phenyl]borate, 97% (R,S)-(COD)Ir[iPr
CAS No.	1195511-66-0
Molecular Formula	C71H60BF24IrNOP
Molecular Weight	~1620.93 g/mol
Synonyms	(R,S)-(COD)Ir[iPr; Ir-iPr-SpiroBIP; Iridium(I) (1,5-cyclooctadiene){(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-(isopropyl)oxazole} tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; Chiral Iridium Spiro Complex; Asymmetric Hydrogenation Catalyst Precursor; Ir(S)-iPr-SpiroBIP BArF; [Ir(COD)((S)-iPr-SpiroBIP)]BArF
EINECS	Contact for details

Quality Control

Our 97% grade product is manufactured under controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including NMR and HPLC analysis, to confirm identity, purity, and enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient light should be avoided.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.