Description

3-Pyridinecarboximidic Acid, Trimethylsilyl Ester is a specialized organosilicon-protected reagent used as a key synthetic intermediate in advanced organic chemistry. Its primary value lies in enabling the controlled introduction of the pyridinecarboximidate moiety, a crucial step in constructing complex heterocyclic and pharmaceutical compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific heterocyclic structures are required for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling and other transformative reactions.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its functional group versatility.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring protected imidate chemistry.

Basic Information

Product Name	3-Pyridinecarboximidic Acid, Trimethylsilyl Ester
CAS No.	959297-97-3
Molecular Formula	C9H14N2OSi
Molecular Weight	194.31 g/mol
Synonyms	Trimethylsilyl 3-pyridinecarboximidate; 3-Pyridinecarboximidic Acid Trimethylsilyl Ester; Nicotinimidic Acid Trimethylsilyl Ester; TMS-Nicotinimidate; 3-(Trimethylsilyloxy)pyridine-1-carboximidate; Pyridine-3-carboximidic Acid TMS Ester; 3-Cyanopyridine TMS Derivative
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarboximidic Acid, Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.