Description

[4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Yl]Methanol is a versatile and high-value heterocyclic building block featuring both amino and hydroxymethyl functional groups. This bifunctional nature makes it a critical intermediate for constructing complex molecular architectures in advanced pharmaceutical synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry & Drug Discovery: Used as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) due to its polar, functionalized tetrahydropyran core.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: The amino and alcohol groups make it a suitable precursor for creating chiral ligands used in asymmetric catalysis.
• Polymer Modification: Can be incorporated into specialty polymers to introduce hydrophilic or reactive sites, enhancing material properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and linkers for studying biological processes and target engagement.

Basic Information

Product Name	[4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Yl]Methanol
CAS No.	959238-22-3
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	4-(Aminomethyl)tetrahydro-2H-pyran-4-methanol; 4-(Hydroxymethyl)-4-(aminomethyl)tetrahydro-2H-pyran; 4-(Aminomethyl)-4-(hydroxymethyl)tetrahydropyran; (4-Hydroxymethyl-tetrahydro-pyran-4-yl)-methylamine; 4-Piperidinemethanol, 4-(aminomethyl)-; 4-(Aminomethyl)tetrahydro-2H-pyran-4-carbinol
EINECS	Contact for details

Quality Control

Our [4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.