Description

Spiro[2H-1-Benzopyran-2,4'-Piperidine]-1'-Carboxylic Acid, 3,4-Dihydro-6-Methyl-4-Oxo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic benzopyran class of compounds. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in central nervous system (CNS) and other specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting neurological pathways.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct spirocyclic frameworks, which are privileged structures in medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for studying structure-activity relationships (SAR) and developing novel synthetic methodologies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Spiro[2H-1-Benzopyran-2,4'-Piperidine]-1'-Carboxylic Acid, 3,4-Dihydro-6-Methyl-4-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	958575-85-4
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	tert-Butyl 3,4-dihydro-6-methyl-4-oxospiro[2H-1-benzopyran-2,4'-piperidine]-1'-carboxylate; 1'-BOC-6-Methyl-4-oxospiro[chromene-2,4'-piperidine]; 1,1-Dimethylethyl 3,4-dihydro-6-methyl-4-oxospiro[2H-1-benzopyran-2,4'-piperidine]-1'-carboxylate; Spiro[chromene-2,4'-piperidine]-1'-carboxylic acid, 3,4-dihydro-6-methyl-4-oxo-, 1,1-dimethylethyl ester; BOC-protected 6-methyl-4-oxospiro[chromene-2,4'-piperidine]
EINECS	Contact for details

Quality Control

Our Spiro[2H-1-Benzopyran-2,4'-Piperidine]-1'-Carboxylic Acid, 3,4-Dihydro-6-Methyl-4-Oxo-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to elevated temperatures.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.