Description

1-(2-Bromoethyl)-2-Chloro-4-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring reactive bromoethyl and chloro-fluoro substituents, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a halogenated phenyl-ethyl moiety.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the specific halogen pattern influences biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine or nitrogen-based ligands used in catalytic processes.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers and liquid crystals.
• Cross-Coupling Reactions: The bromoethyl group acts as an effective handle for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry Studies: Valuable substrate for investigating the effects of fluorine substitution on reactivity and physical properties in aromatic systems.

Basic Information

Product Name	1-(2-Bromoethyl)-2-Chloro-4-Fluorobenzene
CAS No.	958027-89-9
Molecular Formula	C8H7BrClF
Molecular Weight	237.50 g/mol
Synonyms	2-Chloro-4-fluoro-1-(2-bromoethyl)benzene; 1-Bromo-2-(2-chloro-4-fluorophenyl)ethane; 2-(2-Bromoethyl)-1-chloro-4-fluorobenzene; (2-Bromoethyl)-2-chloro-4-fluorobenzene; 2-Chloro-4-fluorophenethyl bromide; 958027-89-9; Benzene, 1-(2-bromoethyl)-2-chloro-4-fluoro-
EINECS	Contact for details

Quality Control

Our 1-(2-Bromoethyl)-2-Chloro-4-Fluorobenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.