Description

cis-4-(2,2,3-Trimethylcyclopentyl)Butanoic Acid is a high-purity, synthetically derived carboxylic acid featuring a unique, rigid cyclopentane backbone. This compound serves as a versatile chiral building block and intermediate in advanced organic synthesis, prized for its structural complexity and defined stereochemistry. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Building block for creating novel pesticides, herbicides, and plant growth regulators with enhanced efficacy and selectivity.
• Fragrance and Flavor Chemistry: Intermediate for synthesizing high-value aroma chemicals with complex, woody, or amber notes due to its trimethylcyclopentyl structure.
• Material Science Research: Monomer or modifier in the development of specialized polymers, resins, and liquid crystals.
• Catalyst and Ligand Preparation: Precursor for synthesizing chiral ligands used in asymmetric catalysis.
• Academic and Industrial R&D: Reference standard and starting material for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	cis-4-(2,2,3-Trimethylcyclopentyl)Butanoic Acid
CAS No.	957136-80-0
Molecular Formula	C12H22O2
Molecular Weight	198.30 g/mol
Synonyms	cis-4-(2,2,3-Trimethylcyclopentyl)butyric acid; (3aS,6R)-2,2,3-Trimethyl-3a,4,5,6-tetrahydro-3H-indene-6-carboxylic acid; 4-[(1S,2R)-2,2,3-Trimethylcyclopentyl]butanoic acid; 2,2,3-Trimethylcyclopentane butanoic acid; TMCPBA; GR-255000 (related derivative); Chiral cyclopentyl butanoic acid intermediate.
EINECS	Contact for details

Quality Control

Our production of cis-4-(2,2,3-Trimethylcyclopentyl)Butanoic Acid adheres to stringent in-process controls and final release testing. Each batch is analyzed to ensure high chemical and chiral purity, with specifications typically meeting or exceeding 97% purity (by HPLC). Our quality system is designed to support cGMP and ISO 9001 standards for traceability and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, impurity profile, and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere (nitrogen or argon), please contact our technical team.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Specific Rotation [α]	Contact for details
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.