Description

2-Bromo-n-Butyl-4-(Trifluoromethoxy)Benzenesulfonamide is a specialized organofluorine sulfonamide derivative, a high-value intermediate prized for its unique trifluoromethoxy and bromoalkyl functionalities. This compound matters for its role in facilitating complex molecular transformations, particularly in the synthesis of advanced bioactive molecules where its structural motifs can impart desirable metabolic stability and lipophilicity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use in medicinal chemistry, lead optimization, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced biological activity and environmental stability.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead compound optimization in drug discovery programs.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays due to its reactive bromoalkyl handle, which can be used for further functionalization.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or liquid crystals where the sulfonamide and fluorinated groups can modify material properties.

Basic Information

Product Name	2-Bromo-n-Butyl-4-(Trifluoromethoxy)Benzenesulfonamide
CAS No.	957062-76-9
Molecular Formula	C11H13BrF3NO3S
Molecular Weight	376.19 g/mol
Synonyms	4-(Trifluoromethoxy)-2-(bromobutyl)benzenesulfonamide; 2-Bromobutyl 4-(trifluoromethoxy)benzenesulfonamide; Benzenesulfonamide, 2-bromo-N-butyl-4-(trifluoromethoxy)-; N-Butyl-2-bromo-4-(trifluoromethoxy)benzenesulfonamide; 957062-76-9; 2-Bromo-N-butyl-4-(trifluoromethoxy)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our 2-Bromo-n-Butyl-4-(Trifluoromethoxy)Benzenesulfonamide is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports research reproducibility and process development from discovery through to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.