Description

4-[(1S,2R)-2-(2-Carboxyethyl)-3,3-Dimethylcyclobutyl]Pent-4-Enoic Acid is a high-purity, chiral cyclobutane derivative featuring two carboxylic acid functional groups, making it a valuable and versatile synthetic intermediate. Its precise stereochemistry and bifunctional nature are critical for constructing complex molecular architectures with defined spatial orientation. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications requiring high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and inflammatory pathways.
• Advanced Organic Synthesis: Serves as a precursor for complex natural product analogs and specialty chemicals where the rigid cyclobutane scaffold is desired.
• Ligand and Catalyst Development: Used in the research and development of new chiral ligands or organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein interactions.

Basic Information

Product Name	4-[(1S,2R)-2-(2-Carboxyethyl)-3,3-Dimethylcyclobutyl]Pent-4-Enoic Acid
CAS No.	957055-11-7
Molecular Formula	C14H22O4
Molecular Weight	254.32 g/mol
Synonyms	(1S,2R)-2-(2-Carboxyethyl)-3,3-dimethyl-1-(3-carboxyprop-2-en-1-yl)cyclobutane; (1S,2R)-2-(3-Carboxypropyl)-3,3-dimethyl-1-(2-carboxyvinyl)cyclobutane; 4-[(1S,2R)-2-(2-Carboxyethyl)-3,3-dimethylcyclobutyl]but-3-enoic acid; Chiral Cyclobutane Diacid Derivative; CAS 957055-11-7
EINECS	Contact for details

Quality Control

Every batch of 4-[(1S,2R)-2-(2-Carboxyethyl)-3,3-Dimethylcyclobutyl]Pent-4-Enoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to preserve optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.