Description

α-D-Erythro-Pentofuranose, 4-C-(Hydroxymethyl)-1,2-o-(1-Methylethylidene)-3-o-(2-Naphthalenylmethyl)- is a sophisticated, high-purity carbohydrate derivative and a key chiral building block in advanced organic synthesis. This compound is valued for its complex, protected pentofuranose structure, which provides a versatile scaffold for constructing nucleoside analogs, antiviral agents, and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical development teams working on novel therapeutics, diagnostic probes, and complex carbohydrate chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Glycochemistry Research: Used as a protected sugar derivative for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Probe and Diagnostic Development: Acts as a building block for creating labeled carbohydrate probes used in biochemical assays and diagnostic imaging.
• Process Chemistry: Employed in route development and scale-up for active pharmaceutical ingredients (APIs) requiring specific sugar-based stereochemistry.
• Academic & Industrial R&D: Essential for methodological development in synthetic organic chemistry and carbohydrate science.

Basic Information

Item	Details
Product Name	α-D-Erythro-Pentofuranose, 4-C-(Hydroxymethyl)-1,2-o-(1-Methylethylidene)-3-o-(2-Naphthalenylmethyl)-
CAS No.	956485-07-7
Molecular Formula	C20H24O6
Molecular Weight	360.40 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-(2-naphthylmethyl)-4-C-(hydroxymethyl)-α-D-erythro-pentofuranose; 4-C-Hydroxymethyl-1,2-O-isopropylidene-3-O-(2-naphthylmethyl)-α-D-erythro-pentofuranose; 3-O-(2-Naphthalenylmethyl)-1,2-O-(1-methylethylidene)-α-D-erythro-pentofuranose-4-C-methanol; Protected D-Erythro-Pentofuranose Derivative; Naphthylmethyl-Protected Sugar Intermediate
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity for sensitive research and development applications. Our standard grade meets typical requirements for advanced synthetic use, with comprehensive characterization including HPLC purity, chiral purity analysis, and structural confirmation (NMR, MS). A detailed Certificate of Analysis (COA) is provided with each batch, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.