Description

(2R,4S)-4-Azido-2-Phenyltetrahydro-2H-Pyran CAS NO 955940-39-3 is a chiral, azide-functionalized carbohydrate derivative, serving as a versatile and valuable synthetic intermediate. Its core value lies in its ability to participate in click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, stereochemically defined building blocks for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research.
• Click Chemistry Reagent: Enables efficient, modular bioconjugation and polymer functionalization via its reactive azide group for CuAAC reactions.
• Glycomimetics & Glycobiology Research: Used to create synthetic analogs of sugars for studying carbohydrate-protein interactions and developing glycan-based therapeutics.
• Agrochemical Synthesis: Intermediate in the development of new, more effective pesticides and herbicides with specific chiral activity.
• Material Science: Precursor for functionalized polymers and dendrimers with tailored properties for specialty coatings and smart materials.
• Chemical Biology Probes: Facilitates the labeling and tracking of biomolecules in cellular systems for diagnostic and research applications.

Basic Information

Product Name	(2R,4S)-4-Azido-2-Phenyltetrahydro-2H-Pyran
CAS No.	955940-39-3
Molecular Formula	C11H13N3O
Molecular Weight	203.24 g/mol
Synonyms	(2R,4S)-4-Azido-2-phenyltetrahydro-2H-pyran; 4-Azido-2-phenyltetrahydro-2H-pyran, (2R,4S)-; (2R,4S)-4-Azido-2-phenyltetrahydropyran; 2H-Pyran, tetrahydro-4-azido-2-phenyl-, (2R,4S)-; 955940-39-3; (2R,4S)-4-Azido-2-phenyloxane; Azidophenyltetrahydropyran
EINECS	Contact for details

Quality Control

Our (2R,4S)-4-Azido-2-Phenyltetrahydro-2H-Pyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the presence of the azide functional group, avoid exposure to heat, strong acids, and heavy metals. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.