Description

3-Bromo-4-Methoxy-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block used in advanced organic synthesis. This compound is valued for its precise molecular structure, which enables the introduction of bromo, methoxy, and nitro functional groups in a single, controlled step. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a substituted benzoic acid scaffold.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro functionalities.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes, affinity tags, and photoaffinity labels for biochemical research.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex azo dyes and other colored organic compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create biaryl structures.

Basic Information

Product Name	3-Bromo-4-Methoxy-5-Nitrobenzoic Acid
CAS No.	954815-08-8
Molecular Formula	C8H6BrNO5
Molecular Weight	276.04 g/mol
Synonyms	5-Nitro-3-bromo-4-methoxybenzoic acid; Benzoic acid, 3-bromo-4-methoxy-5-nitro-; 3-Bromo-4-methoxy-5-nitro-benzoic acid; 4-Methoxy-3-bromo-5-nitrobenzoic acid; 954815-08-8
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Methoxy-5-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.