Description

(2-Carbamimidoyl-Benzyl)-Carbamic Acid tert-Butyl Ester CAS NO 954238-46-1 is a high-purity, protected guanidine derivative primarily used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is an essential intermediate for medicinal chemists and process development scientists working on novel therapeutics, including protease inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting enzymatic pathways.
• Protease Inhibitor Development: Serves as a core structural element in the research and production of potential protease inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Peptidomimetic Synthesis: Employed in the construction of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological mechanisms and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects requiring high-purity advanced intermediates.

Basic Information

Item	Detail
Product Name	(2-Carbamimidoyl-Benzyl)-Carbamic Acid tert-Butyl Ester
CAS No.	954238-46-1
Molecular Formula	C13H19N3O2
Molecular Weight	249.31 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-amidinobenzylamine; tert-Butyl (2-carbamimidoylbenzyl)carbamate; 2-[(tert-Butoxycarbonylamino)methyl]benzenecarboximidamide; BOC-2-Amidinobenzylamine; (2-Amidinobenzyl)carbamic Acid tert-Butyl Ester; N-Boc-2-Amidinobenzylamine
EINECS	Contact for details

Quality Control

Our (2-Carbamimidoyl-Benzyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.