Description

1-Bromo-3-(Bromomethyl)-5-(Trifluoromethyl)Benzene is a versatile and highly functionalized aromatic building block of significant importance in advanced organic synthesis. Its value lies in the presence of two distinct bromine substituents and a trifluoromethyl group, which allow for selective and sequential chemical transformations. This compound is primarily needed by R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated or halogenated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl and bromine groups contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis, including cross-coupling reactions.
• Material Science Monomer: Employed in the research and production of advanced polymers and liquid crystals, where its rigid, multi-functionalized benzene ring can impart specific electronic or physical properties.
• Organic Electronic Materials: A valuable building block for synthesizing charge-transport materials, emitters, or host materials used in OLEDs (Organic Light-Emitting Diodes) and other electronic devices.
• Cross-Coupling Reactions: The bromine atoms are excellent handles for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and other complex structures.

Basic Information

Product Name	1-Bromo-3-(Bromomethyl)-5-(Trifluoromethyl)Benzene
CAS No.	954123-46-7
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	3-(Bromomethyl)-5-(trifluoromethyl)bromobenzene; 1,3-Dibromo-5-(trifluoromethyl)benzene (Note: This is a common misnomer, the correct structure has a bromomethyl group); α,3-Dibromo-5-(trifluoromethyl)toluene; 5-(Trifluoromethyl)-1,3-phenylenedibromomethane; (3-Bromo-5-(trifluoromethyl)phenyl)methyl bromide; 3-Bromomethyl-5-trifluoromethylbromobenzene; 1-Bromo-3-bromomethyl-5-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Bromomethyl)-5-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.