Description

1-(4-Fluoro-2-Methylphenyl)-5-Oxopyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrrolidinone carboxylic acid structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily sought after by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting neurological and inflammatory pathways.
• Organic Synthesis Reagent: Used in academic and industrial laboratories for constructing complex heterocyclic frameworks due to its reactive carboxylic acid and lactam functionalities.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging the fluoro-methylphenyl moiety for bioactivity.
• Material Science: Potential monomer or additive in the development of specialized polymers with unique thermal or chemical properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	1-(4-Fluoro-2-Methylphenyl)-5-Oxopyrrolidine-3-Carboxylic Acid
CAS No.	953903-28-1
Molecular Formula	C12H12FNO3
Molecular Weight	237.23 g/mol
Synonyms	5-Oxo-1-(4-fluoro-2-methylphenyl)pyrrolidine-3-carboxylic acid; 1-(4-Fluoro-2-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid; 4-Fluoro-2-methyl-α-oxo-1-pyrrolidinebutanoic acid γ-lactam; 3-Carboxy-1-(4-fluoro-2-methylphenyl)-2-pyrrolidinone; FMP-OCA; 953903-28-1; 1-(4-Fluoro-2-methylphenyl)-2-oxopyrrolidine-4-carboxylic acid (tautomer)
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluoro-2-Methylphenyl)-5-Oxopyrrolidine-3-Carboxylic Acid adheres to stringent internal quality standards designed for pharmaceutical-grade intermediates. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.