Description

2-Butanone, 1-Chloro-4-(Methylthio)- is a specialized organosulfur compound featuring a chlorinated butanone backbone with a methylthio substituent. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for the development of complex molecules in the agrochemical and pharmaceutical sectors. It is primarily sought by R&D chemists and process development teams in fine chemical and active ingredient manufacturing.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its reactive chloro and thioether groups.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), especially those requiring specific sulfur-containing motifs.
• Organic Synthesis Reagent: Serves as a versatile electrophile and synthon in complex organic transformations, including cross-coupling reactions and heterocycle formation.
• Material Science Research: Investigated as a monomer or functionalizing agent for developing specialty polymers with tailored properties.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis, particularly in asymmetric synthesis.

Basic Information

Product Name	2-Butanone, 1-Chloro-4-(Methylthio)-
CAS No.	953045-49-3
Molecular Formula	C5H9ClOS
Molecular Weight	152.64 g/mol
Synonyms	1-Chloro-4-(methylthio)butan-2-one; 4-(Methylthio)-1-chlorobutan-2-one; 1-Chloro-4-methylsulfanylbutan-2-one; 2-Butanone, 1-chloro-4-(methylthio)-; α-Chloro-γ-(methylthio)butyrophenone (incorrect but related); Chloromethylthiobutanone
EINECS	Contact for details

Quality Control

Our production of 2-Butanone, 1-Chloro-4-(Methylthio)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, purity, and impurity profiles. We provide full traceability and Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for extended stability. This product is moisture-sensitive; keep container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.