Description

Apigenin 5-o-β-D-Glucuronide is a specific glucuronide conjugate of the well-known flavonoid apigenin. This compound is of significant interest for its enhanced bioavailability and solubility profile compared to its aglycone counterpart, making it a valuable standard and active ingredient for research and development. It is primarily sought after by manufacturers and researchers in the pharmaceutical, nutraceutical, and cosmeceutical industries for applications in metabolic studies, formulation development, and as a reference material for analytical purposes.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quantification of apigenin metabolites in pharmacokinetic and bioanalytical studies.
• Nutraceutical Ingredient: Incorporated into advanced dietary supplements targeting anti-inflammatory and antioxidant pathways, leveraging its improved absorption characteristics.
• Cosmeceutical Formulations: Applied in skincare products for its potential skin-soothing and protective properties against environmental stressors.
• Biochemical Research: Serves as a key intermediate or substrate in enzymatic studies related to flavonoid metabolism and conjugation pathways.
• Functional Food & Beverage: Used in the fortification of health-focused foods and drinks to enhance their bioactive flavonoid content.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and other chromatographic methods for detecting flavonoid glucuronides in complex matrices.

Basic Information

Product Name	Apigenin 5-o-β-D-Glucuronide
CAS No.	952414-48-1
Molecular Formula	C21H18O11
Molecular Weight	446.36 g/mol
Synonyms	Apigenin 5-O-β-D-glucopyranosiduronic acid; Apigenin 5-O-glucuronide; 5-O-β-D-Glucopyranuronosylapigenin; 4',5,7-Trihydroxyflavone 5-O-β-D-glucuronide; Apigenin-5-O-β-glucuronide; Apigenin 5-O-β-D-Glucopyranosiduronic Acid; 952414-48-1; Apigenin 5-Glucuronide
EINECS	Contact for details

Quality Control

Our Apigenin 5-o-β-D-Glucuronide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.