Description

Ethyl 1-(5-Chloro-6-Oxo-1,6-Dihydro-4-Pyridazinyl)-4-Piperidinecarboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 952183-76-5. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique pyridazinone-piperidine hybrid structure.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for preclinical and clinical API batches.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of proprietary compounds for clients.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and heterocyclic chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 1-(5-Chloro-6-Oxo-1,6-Dihydro-4-Pyridazinyl)-4-Piperidinecarboxylate
CAS No.	952183-76-5
Molecular Formula	C12H16ClN3O3
Molecular Weight	285.73 g/mol
Synonyms	Ethyl 4-[(5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)amino]piperidine-1-carboxylate; 1-(5-Chloro-6-oxo-1,6-dihydro-4-pyridazinyl)-4-piperidinecarboxylic Acid Ethyl Ester; 4-Piperidinecarboxylic acid, 1-(5-chloro-6-oxo-1,6-dihydro-4-pyridazinyl)-, ethyl ester; Ethyl 1-(5-chloro-6-oxo-1,6-dihydro-4-pyridazinyl)isonipecotate; 952183-76-5; UNII-7G8V81P4L2
EINECS	Contact for details

Quality Control

Our Ethyl 1-(5-Chloro-6-Oxo-1,6-Dihydro-4-Pyridazinyl)-4-Piperidinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.