Description

2-(Tetrahydro-2H-Pyridazin-1-Yl)Acetic Acid, N2-Boc Protected is a high-purity, protected synthetic intermediate crucial for advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex nitrogen-containing heterocycles, a core structure in many active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides with specific modes of action.
• Peptidomimetics & PROTACs: Serves as a critical component in the design of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and biological pathways.
• Academic & R&D Laboratories: Essential for methodological development and exploratory synthesis in university and corporate research settings.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale production under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	2-(Tetrahydro-2H-Pyridazin-1-Yl)Acetic Acid, N2-Boc Protected
CAS No.	952183-19-6
Molecular Formula	C11H18N2O4
Molecular Weight	242.27 g/mol
Synonyms	1-Boc-1,2,3,6-tetrahydropyridazine-4-acetic acid; tert-Butyl 2-(carboxymethyl)-1,2,3,6-tetrahydropyridazine-1-carboxylate; N-Boc-1,2,3,6-tetrahydropyridazine-4-acetic acid; 4-(Carboxymethyl)-1,2,3,6-tetrahydropyridazine-1-carboxylic acid tert-butyl ester; 2-(1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridazin-4-yl)acetic acid; Boc-1,2,3,6-tetrahydropyridazine-4-acetic acid; 1,2,3,6-Tetrahydropyridazine-4-acetic acid, 1-Boc protected; 952183-19-6
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-2H-Pyridazin-1-Yl)Acetic Acid, N2-Boc Protected is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality standards, and custom synthesis under cGMP conditions is available for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.