Description

N'-(1H-Indazol-6-Yl)-N,n-Dimethylethanimidamide is a high-purity, non-nucleoside heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the creation of new chemical entities. The product, identified by CAS number 952183-02-7, is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological pathways.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in universities and research institutes for novel heterocyclic chemistry and methodology development.
• High-Throughput Screening Libraries: Incorporated into diverse compound libraries for biological screening against novel targets.

Basic Information

Product Name	N'-(1H-Indazol-6-Yl)-N,n-Dimethylethanimidamide
CAS No.	952183-02-7
Molecular Formula	C12H16N4
Molecular Weight	216.28 g/mol
Synonyms	N'-(1H-Indazol-6-yl)-N,N-dimethylethanimidamide; N-(1H-Indazol-6-yl)-N',N'-dimethylacetamidine; 1H-Indazole-6-carboxamidine, N,N-dimethyl-; Acetamidine, N-(1H-indazol-6-yl)-N',N'-dimethyl-; 952183-02-7; N,N-Dimethyl-N'-(1H-indazol-6-yl)acetamidine; N-(1H-Indazol-6-yl)-N,N-dimethylacetamidine
EINECS	Contact for details

Quality Control

Our N'-(1H-Indazol-6-Yl)-N,n-Dimethylethanimidamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with research-grade material standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.