Description

1-{3-Bromoimidazo[1,2-B]Pyridazin-6-Yl}Pyrrolidine is a high-purity, advanced pharmaceutical intermediate with the CAS number 952182-15-9. This compound is a critical building block in modern medicinal chemistry, valued for its imidazopyridazine core which is a privileged scaffold in drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for kinase-targeted therapies and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Serves as a core structural component for creating potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to improve drug candidate potency and pharmacokinetic properties.
• Biochemical Probe Development: Employed in the design of chemical probes for studying specific biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	1-{3-Bromoimidazo[1,2-B]Pyridazin-6-Yl}Pyrrolidine
CAS No.	952182-15-9
Molecular Formula	C10H10BrN5
Molecular Weight	280.13 g/mol
Synonyms	1-(3-Bromoimidazo[1,2-b]pyridazin-6-yl)pyrrolidine; 3-Bromo-6-(pyrrolidin-1-yl)imidazo[1,2-b]pyridazine; 952182-15-9; 1-(3-bromoimidazo[1,2-b]pyridazin-6-yl)pyrrolidine; Pyrrolidine, 1-(3-bromoimidazo[1,2-b]pyridazin-6-yl)-; SCHEMBL21806227; BRN 12522079; AKOS040759232
EINECS	Contact for details

Quality Control

Our 1-{3-Bromoimidazo[1,2-B]Pyridazin-6-Yl}Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.