Description

1-{Imidazo[1,2-B]Pyridazin-6-Yl}Pyrrolidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas like kinase inhibition and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a privileged structure in the design and synthesis of potential kinase inhibitors for oncology and inflammatory diseases.
• CNS-Active Compound Synthesis: Employed in the research of compounds targeting neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects from milligram to kilogram scale under cGMP or non-GMP conditions.

Basic Information

Product Name	1-{Imidazo[1,2-B]Pyridazin-6-Yl}Pyrrolidine
CAS No.	952182-09-1
Molecular Formula	C10H12N4
Molecular Weight	188.23 g/mol
Synonyms	1-(Imidazo[1,2-b]pyridazin-6-yl)pyrrolidine; 1-(Imidazo[1,2-b]pyridazin-6-yl)pyrrolidine; 1H-Imidazo[1,2-b]pyridazine, 6-(1-pyrrolidinyl)-; 6-(1-Pyrrolidinyl)imidazo[1,2-b]pyridazine; 6-(Pyrrolidin-1-yl)imidazo[1,2-b]pyridazine; Pyrrolidine, 1-(imidazo[1,2-b]pyridazin-6-yl)-; 952182-09-1
EINECS	Contact for details

Quality Control

Our 1-{Imidazo[1,2-B]Pyridazin-6-Yl}Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. For advanced applications, we offer material produced under cGMP guidelines and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.