Description

2,5-Bis-(Trifluoromethyl)Benzenesulfonamide is a high-value, fluorinated aromatic sulfonamide building block. This compound is critical for introducing the unique physicochemical properties of the trifluoromethyl group into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use as a key intermediate in the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for developing novel active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and receptor modulators where the trifluoromethyl group enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its ability to improve compound bioavailability and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics and potential for sulfonamide linkage.
• Chemical Biology & Proteomics: Can be utilized as a scaffold or labeling agent in probe development for studying enzyme activity and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for use in client-directed synthetic routes for novel chemical entities.

Basic Information

Product Name	2,5-Bis-(Trifluoromethyl)Benzenesulfonamide
CAS No.	951625-11-9
Molecular Formula	C8H5F6NO2S
Molecular Weight	293.19 g/mol
Synonyms	2,5-Bis(trifluoromethyl)benzenesulfonamide; 2,5-Bis(trifluoromethyl)benzene-1-sulfonamide; Benzenesulfonamide, 2,5-bis(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-2,5-xylene-ω-sulfonamide
EINECS	Contact for details

Quality Control

Every batch of 2,5-Bis-(Trifluoromethyl)Benzenesulfonamide is produced and analyzed under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by techniques such as HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for advanced research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.