Description

1-Phenyl-3-(1-(2,2,2-Trifluoroacetyl)pyrrolidin-3-yl)urea is a high-purity, advanced pharmaceutical intermediate featuring a unique urea-pyrrolidine scaffold with a trifluoroacetyl group. This compound is valued for its role in medicinal chemistry research, particularly in the development of novel enzyme inhibitors and targeted therapeutics. It is primarily sought by research institutions and pharmaceutical companies engaged in drug discovery programs for oncology, neurology, and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors of enzymes like kinases and proteases due to its urea moiety.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying protein function and cellular signaling mechanisms.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university laboratories for investigating new synthetic methodologies and bioorganic chemistry.

Basic Information

Product Name	1-Phenyl-3-(1-(2,2,2-Trifluoroacetyl)pyrrolidin-3-yl)urea
CAS No.	951623-94-2
Molecular Formula	C13H14F3N3O2
Molecular Weight	301.27 g/mol
Synonyms	N-Phenyl-N'-[1-(2,2,2-trifluoroacetyl)-3-pyrrolidinyl]urea; 1-Phenyl-3-[1-(trifluoroacetyl)-3-pyrrolidinyl]urea; Urea, N-phenyl-N'-[1-(2,2,2-trifluoroacetyl)-3-pyrrolidinyl]-; 951623-94-2; 1-Phenyl-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)urea; 3-[3-(Phenylcarbamoyl)pyrrolidin-1-yl]-1,1,1-trifluoropropan-2-one
EINECS	Contact for details

Quality Control

Our 1-Phenyl-3-(1-(2,2,2-Trifluoroacetyl)pyrrolidin-3-yl)urea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.