Description

3-Iodo-2-Methylbenzyl Bromide is a versatile halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both iodine and bromine substituents, makes it a valuable intermediate for constructing complex molecules through selective cross-coupling and functionalization reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators requiring halogenated aromatic cores.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Building block for creating organic electronic materials, liquid crystals, and advanced polymers with specific optoelectronic properties.
• Cross-Coupling Reactions: Essential substrate for Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and complex aromatic systems.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	3-Iodo-2-Methylbenzyl Bromide
CAS No.	950577-16-9
Molecular Formula	C8H8BrI
Molecular Weight	310.96 g/mol
Synonyms	1-(Bromomethyl)-3-iodo-2-methylbenzene; 2-Methyl-3-iodobenzyl Bromide; (3-Iodo-2-methylphenyl)methyl Bromide; α-Bromo-3-iodo-2-methyltoluene; 3-Iodo-2-methylbenzylbromide; 950577-16-9; 2-Methyl-3-iodo-benzylbromide
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Methylbenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.