Description

Ethanone, 1-(1,3-Dihydro-1,1-Dimethyl-2H-Isoindol-2-Yl)- is a specialized organic compound featuring a ketone group linked to a dimethyl-substituted isoindoline moiety, making it a valuable synthon in advanced chemical synthesis. This compound is critical for research and development in fine chemical and pharmaceutical manufacturing, where its unique structure enables the construction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for use as a key intermediate or building block.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological or metabolic disorders.
• Agrochemical Research: Used in the development and optimization of new crop protection agents, including herbicides and fungicides, leveraging its heterocyclic core.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor or dopant in the creation of electron-transport or emissive layers for advanced display technologies.
• Ligand Synthesis in Catalysis: Employed to construct sophisticated nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis.
• Polymer Modification: Utilized to introduce functional ketone groups into polymer backbones, enhancing properties for specialty coatings or adhesives.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.

Basic Information

Product Name	Ethanone, 1-(1,3-Dihydro-1,1-Dimethyl-2H-Isoindol-2-Yl)-
CAS No.	949594-09-6
Molecular Formula	C12H15NO
Molecular Weight	189.25 g/mol
Synonyms	1-(1,1-Dimethyl-1,3-dihydro-2H-isoindol-2-yl)ethanone; 2-Acetyl-1,1-dimethylisoindoline; 1,1-Dimethyl-2-acetylisoinoline; N/Acetyl-1,1-dimethylisoindoline; 949594-09-6; Ethanone, 1-(1,1-dimethyl-1,3-dihydro-2H-isoindol-2-yl)-; 2-Acetyl-1,1-dimethylisoindole (common misnomer)
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(1,3-Dihydro-1,1-Dimethyl-2H-Isoindol-2-Yl)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. For specific project requirements, we can tailor quality specifications to meet cGMP, ICH Q7, or other relevant pharmaceutical and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.