Description

(R)-2-Methyl-n-(Thiophen-2-Ylmethylene)Propane-2-Sulfinamide CAS NO 948843-32-1 is a high-purity chiral sulfinamide compound, serving as a versatile and critical building block in asymmetric synthesis. Its primary value lies in its role as a chiral auxiliary or ligand, enabling the stereoselective construction of complex molecules with high enantiomeric purity. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Asymmetric Catalysis: Used as a chiral ligand or auxiliary in transition metal-catalyzed reactions, such as asymmetric additions and reductions.
• Agrochemical Synthesis: Employed in the research and development of enantiomerically pure herbicides, fungicides, and insecticides.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and asymmetric synthesis within R&D laboratories.
• Fine Chemical Production: Facilitates the commercial-scale manufacture of specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(R)-2-Methyl-n-(Thiophen-2-Ylmethylene)Propane-2-Sulfinamide
CAS No.	948843-32-1
Molecular Formula	C9H13NOS2
Molecular Weight	215.33 g/mol
Synonyms	(R)-2-Methyl-N-(thiophen-2-ylmethylene)propane-2-sulfinamide; (R)-N-(Thiophen-2-ylmethylene)-2-methylpropane-2-sulfinamide; (R)-tert-Butanesulfinamide thiophene-2-carboxaldimine; (R)-2-Methyl-2-propanesulfinamide, N-[(2-thienyl)methylene]-; tert-Butanesulfinamide, N-[(2-thienyl)methylene]-, (R)-; (R)-N-((Thiophen-2-yl)methylene)-2-methylpropane-2-sulfinamide
EINECS	Contact for details

Quality Control

Our (R)-2-Methyl-n-(Thiophen-2-Ylmethylene)Propane-2-Sulfinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.