Description

3-Buten-2-One, 3-Chloro-4-(1-Methylethoxy)- is a specialized organic intermediate featuring a reactive α,β-unsaturated ketone (enone) moiety and a chlorinated alkoxy aromatic substituent. This unique bifunctional structure makes it a valuable building block for synthesizing complex molecules in advanced chemical research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and fine chemical frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting specific receptor sites.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a monomer or cross-linking agent precursor in the development of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for complex molecule construction, including heterocycles and natural product analogs, via Michael addition or other condensation reactions.
• Ligand and Catalyst Development: Utilized as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Buten-2-One, 3-Chloro-4-(1-Methylethoxy)-
CAS No.	948041-67-6
Molecular Formula	C7H9ClO2
Molecular Weight	160.60 g/mol
Synonyms	3-Chloro-4-isopropoxybut-3-en-2-one; 1-(3-Chloro-4-isopropoxyphenyl)ethenone; 3'-Chloro-4'-isopropoxychalcone precursor; 4-Isopropoxy-3-chlorophenyl vinyl ketone; 3-Chloro-4-(propan-2-yloxy)but-3-en-2-one; But-3-en-2-one, 3-chloro-4-(1-methylethoxy)-; 3-Chloro-4-isopropoxy-3-buten-2-one
EINECS	Contact for details

Quality Control

Our production of 3-Buten-2-One, 3-Chloro-4-(1-Methylethoxy)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We operate under a cGMP-compliant quality system, and our facilities are prepared for audits to meet the exacting standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive enone functionality, prolonged storage should be under an inert atmosphere such as nitrogen to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.