Description

(4-Fmoc-Amino-Tetrahydropyran-4-Yl)-Acetic Acid CAS NO 946716-25-2 is a specialized, high-purity building block used in advanced organic synthesis. This compound is critical for the efficient and controlled construction of complex molecules, particularly in solid-phase peptide synthesis (SPPS) where the Fmoc-protected amino group is essential. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide-based drugs, and other bioactive compounds.

Application

• As a key Fmoc-protected amino acid derivative for solid-phase peptide synthesis (SPPS).
• Building block for the research and development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Intermediate in the synthesis of complex peptidomimetics and constrained peptides.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies.
• Precursor for the synthesis of specialized linkers and scaffolds in combinatorial chemistry.
• Research chemical for developing new bioconjugation techniques and probes.

Basic Information

Product Name	(4-Fmoc-Amino-Tetrahydropyran-4-Yl)-Acetic Acid
CAS No.	946716-25-2
Molecular Formula	C23H25NO6
Molecular Weight	411.45 g/mol
Synonyms	4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]tetrahydro-2H-pyran-4-acetic Acid; 2-[4-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]oxan-4-yl]acetic Acid; Fmoc-Amino-THP-Acetic Acid; (4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)tetrahydro-2H-pyran-4-yl)acetic Acid; Fmoc-Thp(Ac)-OH; Fmoc-4-amino-THP-4-acetic Acid
EINECS	Contact for details

Quality Control

Our (4-Fmoc-Amino-Tetrahydropyran-4-Yl)-Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.