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6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone CAS NO 946385-86-0


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CAS No.:946385-86-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its unique heterocyclic structure, which serves as a critical building block for synthesizing novel bioactive molecules. It is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting specific biological pathways.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
  • Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing potential kinase inhibitors.
  • Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular processes.
  • Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
  • Academic Research: Used in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name 6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone
CAS No. 946385-86-0
Molecular Formula C19H16BrN3O
Molecular Weight 382.26 g/mol
Synonyms 4,5-Dihydro-6-(4-bromophenyl)-4-(1-methyl-1H-indol-3-yl)-3(2H)-pyridazinone; 6-(4-Bromophenyl)-4-(1-methylindol-3-yl)-4,5-dihydropyridazin-3(2H)-one; 4,5-Dihydro-6-(p-bromophenyl)-4-(1-methyl-1H-indol-3-yl)-3(2H)-pyridazinone; 946385-86-0; 3(2H)-Pyridazinone, 4,5-dihydro-6-(4-bromophenyl)-4-(1-methyl-1H-indol-3-yl)-
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Quality Control

Our 6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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