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6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone CAS NO 946385-86-0
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CAS No.:946385-86-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its unique heterocyclic structure, which serves as a critical building block for synthesizing novel bioactive molecules. It is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting specific biological pathways.
- Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
- Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing potential kinase inhibitors.
- Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular processes.
- Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
- Academic Research: Used in university and institutional labs for exploratory research in organic and medicinal chemistry.
Basic Information
| Product Name | 6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone |
| CAS No. | 946385-86-0 |
| Molecular Formula | C19H16BrN3O |
| Molecular Weight | 382.26 g/mol |
| Synonyms | 4,5-Dihydro-6-(4-bromophenyl)-4-(1-methyl-1H-indol-3-yl)-3(2H)-pyridazinone; 6-(4-Bromophenyl)-4-(1-methylindol-3-yl)-4,5-dihydropyridazin-3(2H)-one; 4,5-Dihydro-6-(p-bromophenyl)-4-(1-methyl-1H-indol-3-yl)-3(2H)-pyridazinone; 946385-86-0; 3(2H)-Pyridazinone, 4,5-dihydro-6-(4-bromophenyl)-4-(1-methyl-1H-indol-3-yl)- |
| EINECS | Contact for details |
Quality Control
Our 6-(4-Bromophenyl)-4-(1-Methyl-1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.





