Description

Potassium [1-(tert-Butoxycarbonyl)-1H-Indole-2-Yl]Trifluoroborate is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its exceptional stability and reactivity as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex indole-containing molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing functionalized indole scaffolds for oncology, neurology, and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that leverage the indole structure for enhanced biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysis, and specialty polymers.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a stable, air- and moisture-tolerant boronic acid equivalent for palladium-catalyzed cross-coupling with various aryl/vinyl halides.
• Peptidomimetics & Bioconjugation: Facilitates the introduction of the indole moiety into peptides and other biomolecules for drug design and biochemical probes.
• Academic & R&D Laboratories: A vital reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	Potassium [1-(tert-Butoxycarbonyl)-1H-Indole-2-Yl]Trifluoroborate
CAS No.	945493-51-6
Molecular Formula	C₁₃H₁₄BF₃KNO₂
Molecular Weight	325.16 g/mol
Synonyms	Potassium (1-Boc-indol-2-yl)trifluoroborate; 1-Boc-2-indolyltrifluoroborate potassium salt; Potassium 1-(tert-Butoxycarbonyl)-1H-indol-2-yltrifluoroborate; 1-(tert-Butoxycarbonyl)-1H-indole-2-yltrifluoroborate potassium salt; 2-Trifluoroboratomethyl-1-Boc-indole potassium salt; Potassium 1-Boc-2-indolyltrifluoroboronate; (1-Boc-1H-indol-2-yl)-trifluoro-boranuide potassium
EINECS	Contact for details

Quality Control

Our Potassium [1-(tert-Butoxycarbonyl)-1H-Indole-2-Yl]Trifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and KF titration. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon/nitrogen) when opening to prevent decomposition. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
NMR Purity (¹H NMR)	≥95%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.