Description

(6Ar,8S,10As)-10A-(4-Chlorophenylsulfonyl)-1,4-Difluoro-6A,7,8,9,10,10A-Hexahydro-6H-Benzo[C]Chromen-8-Ol is a high-purity, advanced pharmaceutical intermediate characterized by a complex, multi-ring molecular structure featuring sulfonyl and fluorine substituents. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with targeted biological activity. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors focused on developing new small-molecule drugs.

Application

This specialized intermediate serves as a key precursor in sophisticated organic synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate properties.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for potential drug candidates.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of complex, proprietary molecules.

Basic Information

Product Name	(6Ar,8S,10As)-10A-(4-Chlorophenylsulfonyl)-1,4-Difluoro-6A,7,8,9,10,10A-Hexahydro-6H-Benzo[C]Chromen-8-Ol
CAS No.	944949-06-8
Molecular Formula	C19H17ClF2O4S
Molecular Weight	414.85 g/mol
Synonyms	10A-(4-Chlorophenylsulfonyl)-1,4-difluoro-6A,7,8,9,10,10A-hexahydro-6H-benzo[c]chromen-8-ol; (6ar,8s,10as)-10a-[(4-chlorophenyl)sulfonyl]-1,4-difluoro-6a,7,8,9,10,10a-hexahydro-6h-benzo[c]chromen-8-ol; 1,4-Difluoro-10a-(4-chlorophenylsulfonyl)-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-8-ol; Benzo[c]chromen derivative CAS 944949-06-8; 944949-06-8; SCHEMBL21806227; A1-00826
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) documenting full specifications are available upon request. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.