Description

2-Bromo-6-Chloro-Imidazo[1,2-B]Pyridazine is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery. This heterocyclic compound serves as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the production of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale synthesis of target molecules during API development.
• Biochemical Tool Compound Synthesis: Serves as a precursor for creating specialized probes and inhibitors used in biological assay development and target validation.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.
• Agrochemical Research: Potential application as an intermediate in the discovery of new agrochemicals, such as herbicides and fungicides.

Basic Information

Product Name	2-Bromo-6-Chloro-Imidazo[1,2-B]Pyridazine
CAS No.	944902-75-4
Molecular Formula	C6H3BrClN3
Molecular Weight	232.47 g/mol
Synonyms	2-Bromo-6-chloroimidazo[1,2-b]pyridazine; Imidazo[1,2-b]pyridazine, 2-bromo-6-chloro-; 6-Chloro-2-bromoimidazo[1,2-b]pyridazine; 2-Bromo-6-chloro-[1,2,4]triazolo[1,5-a]pyridine (common misnomer); 2-Br-6-Cl-Imidazopyridazine; BCPI
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloro-Imidazo[1,2-B]Pyridazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.