Description

(1R,5S)-3-Benzyl-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane-2,4-Dione CAS NO 943516-53-8 is a high-purity, advanced pharmaceutical intermediate featuring a unique, constrained bicyclic structure. This compound is of significant value for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and antiviral drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of proprietary drug candidates.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures with high stereochemical control.
• Research & Development (R&D): Employed in academic and industrial labs for method development and exploring new chemical entities.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of target molecules.
• Asymmetric Synthesis: Acts as a precursor or template in catalytic asymmetric reactions to introduce specific stereocenters.

Basic Information

Product Name	(1R,5S)-3-Benzyl-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane-2,4-Dione
CAS No.	943516-53-8
Molecular Formula	C16H17NO2
Molecular Weight	255.31 g/mol
Synonyms	(1R,5S)-3-Benzyl-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione; 3-Benzyl-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione; (1R,5S)-rel-3-Benzyl-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione; 943516-53-8; Bicyclo[3.1.0]hexane-2,4-dione derivative; 3-Azabicyclo[3.1.0]hexane-2,4-dione, 3-benzyl-6,6-dimethyl-, (1R,5S)-
EINECS	Contact for details

Quality Control

Our (1R,5S)-3-Benzyl-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.