Description

(S)-2-((tert-Butoxycarbonyl)Amino)-3-(3-Carbamoylphenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group and a carbamoylphenyl side chain. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams in the development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a protected phenylalanine analog with a polar carboxamide functional group.
• Protease Inhibitor Development: Serves as a core structural component in the design of inhibitors for proteolytic enzymes.
• Chemical Biology Research: Employed as a tool compound for studying protein-protein interactions and signal transduction pathways.
• Bioconjugation: The carboxylic acid and carbamoyl groups provide handles for conjugation to other molecules, carriers, or surfaces.
• Library Synthesis: Used in combinatorial chemistry and high-throughput screening to create diverse libraries of bioactive compounds.

Basic Information

Product Name	(S)-2-((tert-Butoxycarbonyl)Amino)-3-(3-Carbamoylphenyl)Propanoic Acid
CAS No.	943449-15-8
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	Boc-3-AmPhe-OH; (S)-2-(Boc-Amino)-3-(3-carbamoylphenyl)propanoic acid; Boc-L-3-AmPhe-OH; N-Boc-3-amino-L-phenylalanine; N-α-(tert-Butoxycarbonyl)-3-carbamoyl-L-phenylalanine; tert-Butyl (S)-(1-carboxy-2-(3-carbamoylphenyl)ethyl)carbamate; (S)-3-(3-Carbamoylphenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-((tert-Butoxycarbonyl)Amino)-3-(3-Carbamoylphenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.