Description

n-[(2S)-2-Amino-2-Phenylethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is a chiral, protected amino acid derivative of significant value in advanced organic synthesis. This compound serves as a critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector who require high-purity, stereochemically defined intermediates for peptide mimetics, active pharmaceutical ingredients (APIs), and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce a protected phenylethylamine moiety.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct stereogenic centers.
• Protease Inhibitor Development: Serves as a core structural element in the design and synthesis of enzyme inhibitors.
• Chemical Biology Research: Utilized in the preparation of molecular probes and labeled compounds for studying biological pathways.
• Agrochemical Synthesis: Potential intermediate in the development of chiral, biologically active crop protection agents.

Basic Information

Product Name	n-[(2S)-2-Amino-2-Phenylethyl]-Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	943322-87-0
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-2-phenylethanamine; (S)-2-Amino-2-phenylethylcarbamic acid tert-butyl ester; Boc-(S)-2-Amino-2-phenylethylamine; tert-Butyl N-[(2S)-2-amino-2-phenylethyl]carbamate; (S)-tert-Butyl (2-amino-2-phenylethyl)carbamate; (S)-Boc-2-Amino-2-phenylethylamine; (S)-1-Boc-amino-2-phenylethylamine
EINECS	Contact for details

Quality Control

Our production of n-[(2S)-2-Amino-2-Phenylethyl]-Carbamic Acid 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and cGMP manufacturing. All materials are characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.