Description

4-(4-Bromo-3-(((Tetrahydro-2H-Pyran-2-Yl)Oxy)Methyl)Phenoxy)Benzonitrile is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture designed for sophisticated synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), enabling precise chemical modifications. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, particularly for projects involving brominated aromatic systems and protected alcohol functionalities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Organic Synthesis Building Block: Serves as a versatile substrate for further functionalization, including cross-coupling reactions and nucleophilic substitutions.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced crop protection chemicals and herbicides.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced pharmaceutical development.

Basic Information

Item	Detail
Product Name	4-(4-Bromo-3-(((Tetrahydro-2H-Pyran-2-Yl)Oxy)Methyl)Phenoxy)Benzonitrile
CAS No.	943311-78-2
Molecular Formula	C19H18BrNO3
Molecular Weight	388.26 g/mol
Synonyms	4-(4-Bromo-3-((Tetrahydro-2H-pyran-2-yloxy)methyl)phenoxy)benzonitrile; 4-(4-Bromo-3-(((THP)Oxy)Methyl)Phenoxy)Benzonitrile; Benzonitrile, 4-[4-bromo-3-[[(tetrahydro-2H-pyran-2-yl)oxy]methyl]phenoxy]-; 4-(4-Bromo-3-((THP-O-CH2)-phenoxy)benzonitrile; 4-(4-Bromo-3-(THPoxymethyl)phenoxy)benzonitrile; CAS 943311-78-2
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-3-(((Tetrahydro-2H-Pyran-2-Yl)Oxy)Methyl)Phenoxy)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.