Description

Carbamic Acid, n-3-Azetidinyl-n-Methyl-, 1,1-Dimethylethyl Ester, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate with the CAS number 943060-59-1. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in producing complex, nitrogen-containing heterocyclic compounds.

Application

This specialized intermediate serves as a key building block in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used for constructing complex azetidine and carbamate-containing molecular frameworks in medicinal chemistry.
• Research & Development: Essential for academic and industrial research focused on developing new chemical entities and exploring structure-activity relationships.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of high-value fine chemicals and APIs.

Basic Information

Product Name	Carbamic Acid, n-3-Azetidinyl-n-Methyl-, 1,1-Dimethylethyl Ester, Hydrochloride (1:1)
CAS No.	943060-59-1
Molecular Formula	C9H19ClN2O2
Molecular Weight	222.71 g/mol
Synonyms	tert-Butyl (3-(methylamino)azetidin-1-yl)carbamate hydrochloride; 1,1-Dimethylethyl N-[3-(methylamino)-1-azetidinyl]carbamate hydrochloride; N-3-Azetidinyl-N-methylcarbamic Acid tert-Butyl Ester Hydrochloride; (3-(Methylamino)azetidin-1-yl)carbamic Acid tert-Butyl Ester Hydrochloride; tert-Butyl 3-(methylamino)azetidine-1-carboxylate hydrochloride; BOC-3-(Methylamino)azetidine Hydrochloride; 943060-59-1
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-3-Azetidinyl-n-Methyl-, 1,1-Dimethylethyl Ester, Hydrochloride (1:1) adheres to stringent quality management systems. Each batch is manufactured under controlled conditions and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.