Description

Bicyclo[2.2.2]Octane-1-Acetic Acid, 4-[4-(4-Amino-7,7-Dimethyl-7H-Pyrimido[4,5-B][1,4]Oxazin-6-Yl)Phenyl]- ,Acoh Salt is a high-purity, complex heterocyclic compound with a bicyclo[2.2.2]octane core, serving as a critical advanced pharmaceutical intermediate or research chemical for the development of novel therapeutic agents. Its unique fused pyrimido-oxazine structure makes it a valuable scaffold for medicinal chemistry, particularly in targeting specific enzymes or receptors. This compound is essential for R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) or oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Development: Serves as a precursor for creating labeled compounds or probes to study biological pathways and protein interactions.
• Organic Synthesis: Employed in advanced organic reactions to construct complex molecular architectures due to its rigid bicyclic framework.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for cutting-edge chemical and pharmacological research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and process development.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-1-Acetic Acid, 4-[4-(4-Amino-7,7-Dimethyl-7H-Pyrimido[4,5-B][1,4]Oxazin-6-Yl)Phenyl]- ,Acoh Salt
CAS No.	942999-67-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]bicyclo[2.2.2]octane-1-acetic acid acetate salt; Bicyclo[2.2.2]octane-1-acetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]-, acetate; Acetic acid, compound with 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]bicyclo[2.2.2]octane-1-acetic acid (1:1); CAS 942999-67-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support cGMP compliance for applications requiring regulatory filing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.