Description

3-[4-[1-Ethyl-3-(4-Nitrophenyl)-1H-Pyrazol-4-Yl]-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of new drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of investigational new drugs (INDs) and new chemical entities (NCEs), especially those targeting specific kinase pathways.
• Oncology Research: Serves as a core scaffold for developing potential small-molecule inhibitors for cancer treatment, leveraging its fused pyrazole and pyrrolopyridine motifs.
• Antiviral Drug Development: Used in research programs aimed at creating novel antiviral compounds due to the structural features common in protease or polymerase inhibitors.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tagged ligand in studying protein-ligand interactions and cellular signaling mechanisms.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules for specialized applications.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in medicinal chemistry and organic synthesis methodologies.

Basic Information

Product Name	3-[4-[1-Ethyl-3-(4-Nitrophenyl)-1H-Pyrazol-4-Yl]-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]Benzaldehyde
CAS No.	942920-00-5
Molecular Formula	C33H25N5O4S
Molecular Weight	587.65 g/mol
Synonyms	3-[4-[1-Ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]benzaldehyde; 942920-00-5; 3-(4-(1-Ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)benzaldehyde; Benzaldehyde, 3-[4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-
EINECS	Contact for details

Quality Control

Our 3-[4-[1-Ethyl-3-(4-Nitrophenyl)-1H-Pyrazol-4-Yl]-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container is opened.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.