Description

6-Bromo-4-Oxo-n-{4-[4-(Propan-2-Yl)Phenyl]-1,2,5-Oxadiazol-3-Yl}-4H-Chromene-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and inflammation research. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies due to its specific molecular scaffold.
• Anti-inflammatory Drug Development: Serves as a core structure for compounds targeting inflammatory pathways.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag to study protein-ligand interactions and enzyme function.
• Academic & Institutional Research: Utilized in universities and research institutes for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) offering custom synthesis services from milligram to kilogram scale.

Basic Information

Product Name	6-Bromo-4-Oxo-n-{4-[4-(Propan-2-Yl)Phenyl]-1,2,5-Oxadiazol-3-Yl}-4H-Chromene-2-Carboxamide
CAS No.	942894-93-1
Molecular Formula	C22H16BrN3O4
Molecular Weight	466.29 g/mol
Synonyms	6-Bromo-4-oxo-N-[4-[4-(propan-2-yl)phenyl]-1,2,5-oxadiazol-3-yl]-4H-chromene-2-carboxamide; 6-Bromo-4-oxo-N-(4-(4-isopropylphenyl)-1,2,5-oxadiazol-3-yl)-4H-chromene-2-carboxamide; 4H-Chromene-2-carboxamide, 6-bromo-4-oxo-N-[4-[4-(1-methylethyl)phenyl]-1,2,5-oxadiazol-3-yl]-; 942894-93-1; 6-Bromo-4-oxo-N-(4-(p-isopropylphenyl)-1,2,5-oxadiazol-3-yl)chromene-2-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Oxo-n-{4-[4-(Propan-2-Yl)Phenyl]-1,2,5-Oxadiazol-3-Yl}-4H-Chromene-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.