Description

1-(2,2,2-Trifluoro-n-Phenylacetimidate)-2,3,4,6-Tetra-o-Acetyl-D-Glucopyranoside is a high-purity, advanced glycosylation reagent and synthetic intermediate critical for modern organic and medicinal chemistry. Its primary value lies in enabling the efficient and selective introduction of complex, fluorinated sugar moieties into target molecules, a key step in developing novel pharmaceuticals and bioactive compounds. This product is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical synthesis, and advanced material science who require reliable, high-quality building blocks for glycosylation reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel glycosylated drug candidates, including antiviral and anticancer agents.
• Glycobiology Research: Used as a specialized reagent for studying carbohydrate-protein interactions and enzymatic processes.
• Agrochemical Synthesis: Intermediate in the development of advanced, fluorinated pesticides and herbicides with enhanced activity.
• Fluorinated Sugar Analog Production: Serves as a precursor for creating a range of trifluoromethylated carbohydrate analogs for various applications.
• Chemical Biology Probe Development: Utilized in the creation of activity-based probes and diagnostic tools targeting glycosidases and glycosyltransferases.
• Complex Oligosaccharide Synthesis: A critical reagent in the multi-step synthesis of complex, fluorinated oligosaccharides.

Basic Information

Product Name	1-(2,2,2-Trifluoro-n-Phenylacetimidate)-2,3,4,6-Tetra-o-Acetyl-D-Glucopyranoside
CAS No.	942428-83-3
Molecular Formula	C22H24F3NO10
Molecular Weight	519.42 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl 2,2,2-trifluoro-N-phenylacetimidate; 1-(2,2,2-Trifluoro-N-phenylacetimidoyl)-2,3,4,6-tetra-O-acetyl-β-D-glucopyranose; Phenyl 2,3,4,6-tetra-O-acetyl-1-deoxy-1-(2,2,2-trifluoroacetimidoyl)-α-D-glucopyranoside; Glycosyl Trifluoroacetimidate Donor; TFAI Glycosylation Reagent; α-D-Glucopyranoside, 1-(2,2,2-trifluoro-N-phenylacetimidate)-2,3,4,6-tetraacetate
EINECS	Contact for details

Quality Control

Our 1-(2,2,2-Trifluoro-n-Phenylacetimidate)-2,3,4,6-Tetra-o-Acetyl-D-Glucopyranoside is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under inert atmosphere when appropriate to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.