Description

4-tert-Butyl-2-Iodo-1-Nitrobenzene is a high-purity, multi-functional aromatic intermediate designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a sterically hindered tert-butyl group with reactive iodine and nitro substituents, enabling precise and selective chemical transformations. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic cores for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, where the iodine atom serves as a versatile handle for cross-coupling reactions.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Advanced Material Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive materials due to its electron-withdrawing nitro group and potential for further derivatization.
• Chemical Biology Probes: Useful for tagging and modifying biomolecules in research applications, leveraging the reactivity of the iodine atom for bioconjugation.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, structurally complex intermediates.

Basic Information

Product Name	4-tert-Butyl-2-Iodo-1-Nitrobenzene
CAS No.	942204-75-3
Molecular Formula	C10H12INO2
Molecular Weight	305.11 g/mol
Synonyms	1-tert-Butyl-4-iodo-2-nitrobenzene; 2-Iodo-4-tert-butylnitrobenzene; 4-(tert-Butyl)-2-iodonitrobenzene; 4-tert-Butyl-2-iodonitrobenzene; 2-Nitro-4-tert-butyl-1-iodobenzene; 1-Iodo-2-nitro-4-tert-butylbenzene; 4-(1,1-Dimethylethyl)-2-iodo-1-nitrobenzene
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-2-Iodo-1-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. For custom grades or specific purity requirements, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.