Description

(2S)-2-Amino-3-(Tetrahydro-2H-Pyran-3-Yl)Propan-1-Ol is a chiral, non-proteinogenic amino alcohol derivative featuring a tetrahydro-2H-pyran (oxane) ring, serving as a sophisticated building block in advanced organic synthesis. Its unique structure makes it a valuable intermediate for constructing complex molecules with precise stereochemistry, which is critical for developing bioactive compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for applications requiring specific enantiomeric control and molecular complexity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Peptidomimetics and Bio-conjugates: Incorporated into peptide analogs and bioconjugation linkers to modulate stability, bioavailability, and target specificity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Advanced Material Science: A potential monomer or modifier for creating specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	(2S)-2-Amino-3-(Tetrahydro-2H-Pyran-3-Yl)Propan-1-Ol
CAS No.	942144-41-4
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	(2S)-2-Amino-3-(Oxan-3-yl)propan-1-ol; 3-(Tetrahydro-2H-pyran-3-yl)-L-alaninol; L-3-(Tetrahydro-2H-pyran-3-yl)alanol; (S)-2-Amino-3-(tetrahydro-2H-pyran-3-yl)propan-1-ol; 942144-41-4; (S)-3-(Tetrahydro-2H-pyran-3-yl)alaninol; 2-Amino-3-(tetrahydro-2H-pyran-3-yl)-1-propanol, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-3-(Tetrahydro-2H-Pyran-3-Yl)Propan-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We employ advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to verify specifications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.