Description

Methyl6-Bromo-5-Acetamido-3,4-Dihydro-2H-1-Benzopyran-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated dihydrobenzopyran structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel therapeutic agents. It is primarily sought after by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Serves as a building block in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Process Chemistry: Employed in route scouting and process optimization for efficient, scalable manufacturing of target molecules.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	Methyl6-Bromo-5-Acetamido-3,4-Dihydro-2H-1-Benzopyran-8-Carboxylate
CAS No.	941692-26-8
Molecular Formula	C13H14BrNO4
Molecular Weight	328.16 g/mol
Synonyms	Methyl 6-bromo-5-acetamido-3,4-dihydro-2H-1-benzopyran-8-carboxylate; 8-Carbomethoxy-6-bromo-5-acetamido-3,4-dihydro-2H-1-benzopyran; 6-Bromo-5-acetamido-3,4-dihydro-8-methoxycarbonyl-2H-1-benzopyran; Methyl 6-bromo-5-(acetylamino)-3,4-dihydro-2H-chromene-8-carboxylate; 941692-26-8; 6-Bromo-5-acetamidochroman-8-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl6-Bromo-5-Acetamido-3,4-Dihydro-2H-1-Benzopyran-8-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.